About Hydrea 500mg
hydrea 500mg Capsule is an orally active anticancer agent which is used alone or in combination with other cancer drugs or radiotherapy for the treatment of various chronic myeloid leukemia and cancers of the head, neck, and cervix. It is also used in reducing the painful crisis and reduce the need for blood transfusions in adults and children (2 years of age and older) with sickle cell anemia.
Hydrea 500Mg Capsule is an oral medicene that is prescribed to patients suffering from chronic myelogenous leukemia, acute myelogenous leukemia, sickle-cell disease, ovarian cancer, cervical cancer, and polycythemia vera. This Capsule slows down the growth of cancer cells in the body and can reduce the need for blood tranfusion. It comes as a capsule that is usually taken once in a day. But talk to your doctor regarding the right dosage for you.
Common side effects of Hydrea 500Mg Capsule drug are fever, loss of appetite, shortness of breath, headache, drowsiness, nausea, vomiting, bone marrow suppression, psychiatric problems. Contact your doctor if you notice any unusual symptoms such as dizziness, confusion, joint pain, seizures, tarry stools, sores in the mouth or unusual bleeding.
Do not use this medicine if; you are allergic to any of its ingredients; have a prescription for didanosine or stavudine; have severe bone marrow depressin; have anemia or count of white blood cells or platelets is low. Also, let your healthcare provider know before prescription if- you are pregnant or are planning to become pregnant, are breastfeeding, have a history of allergies to food or medicine, have anemia, kidney or liver problems or if you are a HIV positive patient.It is advicable to consult a Hematologist before using this medicine.
How Dose Medicine Works?
Hydrea 500Mg Capsule is an antineoplastic agent. It converts to a free radical and inhibits the entire DNA replicase complex, including ribonucleotide reductase and selectively inhibits DNA synthesis, while also inhibiting DNA repair mechanisms. This leads to death of neoplastic cells.
Cancerous cells lose this ability.The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).They also induce cell suicide (self-death or apoptosis).Unfortunately, chemotherapy does not know the difference between the cancerous cells and the normal cells.
What Hydrea 500mg Is Used For
- Chronic myeloid leukemia
- Essential thrombocytosis and polycythemia vera
- Head and neck cancer (used with radiation therapy)
When not to Use?
This medicine is not recommended for use in patients with a known allergy to hydroxyurea, or any other inactive ingredients present along with it.
This medicine is not recommended for use in pregnant women due to the increased risk of birth defects.
Bone marrow suppression
This medicine is not recommended for use in patients with bone marrow suppression due to the increased risk of worsening of the patient’s condition.
Hydrea 500mg Dosage
Your dose will be based on your weight, medical condition, and response to treatment.The medicine is usually taken once a day.When hydrea 500 is used to treat certain types of cancer, it’s sometimes taken once every three days.Try to take the drug around the same time each day.Don’t crush, chew, or split the capsules.
Hydrea 500mg Overdose
Symptoms of a hydroxyurea overdose may include:
- Pain, redness, swelling, or scaling on the hands and feet
- Sores in the mouth and throat
- Darkening of the skin
Hydrea 500mg Missed Dose
- If you miss a dose of hydrea, take it as soon as you remember.
- But skip the missed dose if it’s almost time for your next scheduled dose.
- Don’t take extra medicine to make up for a missed dose.
Hydrea 500mg Side effects
- Nausea and Vomiting
- Loss of appetite
- Chills and fever
- Hair loss
- Lower back or side pain
Hydrea 500mg Warnings
Warnings for special population
hydrea 500 mg uses is not recommended for use in pregnant women unless absolutely necessary.
Hydrea 500mg is not recommended for use in breastfeeding women. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition
This medicine causes may cause bone marrow suppression which in turn lowers the white blood cell count (neutrophils) and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the counts are lower than the reference range.
This medicine is known to cause secondary cancers especially leukemia and skin cancers. Close monitoring of signs and symptoms is necessary. The treatment should be discontinued if malignancy develops. Avoid exposure to sunlight or tanning beds.
This medicine is known to cause blood vessel toxicities like vasculitic ulcerations and gangrene, especially in patients who are on interferon therapy. Close monitoring of signs and symptoms is necessary. The treatment should be discontinued if any vascular toxicities develop.
Hydrea 500mg Precautions
- Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
- Pregnancy category D (Hydroxyurea may be hazardous to the fetus.
- Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.
- Do not breast feed while taking hydrea 500 mg substitute.
- If powder from a capsule spills, it should be wiped with a damp disposable towel, placed in a plastic bag, and discarded. Hands should be washed thoroughly.